The Fifth China Conference on the Development of Edible and Medicinal Fungi Industry opened

On December 13, 2019, the Fifth China Conference on the Development of Edible and Medicinal Fungi Industry (hereinafter referred to as "the Congress"), a biennial event of China's edible and medical fungus industry, was held in Huacheng, Guangzhou.

With the theme of "the development of edible and medicinal bacteria industry and the manufacture of microbial food", more than 20 top scientists shared and discussed the cutting-edge scientific research achievements of edible and medicinal fungi.

Wu Qingping, academician of the Chinese Academy of Engineering and chairman of the Congress.

The conference is sponsored by China Edible Mushroom Association, National Microbiological seed Industry Technology Innovation Strategic Alliance, Guangdong Institute of Microbiology and Guangdong Microbiology Society; Guangdong Edible Mushroom Industry Association and Guangdong Yuewei Edible Mushroom Technology Co., Ltd., Guangdong Huankai Microbiological Science and Technology Co., Ltd., Guangdong Old Science and Technology Workers Association (Nanshan Science Forum).

The speakers from top to bottom and from left to right are Gao Maolin, executive vice president of China Edible Fungi Association, Dai Bingye, deputy director of China Rural Technology Development Center of the Ministry of Science and Technology, researcher Guo Jun, director of South China State key Laboratory of Applied Microbiology, and Huang Binmin, deputy director of Guangdong Agricultural and Rural Department.

Academician Wu Qingping, chairman of the Congress, Gao Maolin, executive vice president of the China Edible Fungi Association, Dai Bingye, deputy director of the China Rural Technology Development Center of the Ministry of Science and Technology, Huang Binmin, deputy director of the Agricultural and Rural Department of Guangdong Province, Lin Guangmei, director of the Department of Science and Technology of Guangdong Province, Guo Jun, director of the State key Laboratory of Applied Microbiology in South China, and other academicians and government guests from the fields of edible medicinal fungi, food processing, biology and great health,

More than 300 important guests, including well-known experts, media representatives, industry scholars and entrepreneurs, gathered together.It provides a new vision for the development of national food and medicine bacteria industry and large health industry.

Edible and medicinal fungi are a treasure house of resources that need to be explored urgently.

At the meeting, Academician Wu Qingping, chairman of the conference, pointed out that edible and medicinal fungi are not only a treasure house of resources that need to be explored urgently, but also a treasure of natural active drugs. China is rich in edible mushroom resources. Among the more than 100000 species of macrofungi, even more than 1200 species have been proved to be edible, among which less than 10% are artificially cultivated edible fungi, and only 20 or 30 species such as Lentinus edodes, Pleurotus ostreatus, fungus, Ganoderma lucidum and so on are common in the market.There is great potential for resource development.Taking Grifola frondosa polysaccharide F2 and Ganoderma lucidum polysaccharide F31 as examples, Academician Wu Qingping deeply expounded the function of edible fungus polysaccharide.

Academician Wu Qingping made a report

In recent years, Guangdong Institute of Microbiology has made use of the leading position of science and technology in the national edible and pharmaceutical fungus industry and the advantages of international and domestic cooperation to build the world's largest germplasm bank of edible fungi and macrofungi. At present, more than 11000 strains of wild fungi have been collected and preserved. More than 4300 strains have been identified and more than 80, 000 specimens have been preserved.The artificial domestication and cultivation experiments of batches of varieties were carried out in the National High-tech industrialization Base for the breeding of New varieties of Edible Fungi in Guangzhou Science City.Academician Wu Qingping stressed that the exploration of wild species resources of edible and medicinal fungi and the study of new functional factors will be the key breakthrough direction of the edible and medicinal fungus industry, and will also bring more well-being to human health.

The study of probiotics and intestinal flora has become a hot field in the world."

the study of probiotics, intestinal flora and health and disease has become a hot field all over the world."In view of the standards and safety of probiotics, the regulation mechanism of intestinal flora, and the technical bottlenecks of probiotics and their related industries, Professor Zhang Heping of Inner Mongolia Agricultural University pointed out at the meeting that how to deal with this problem scientifically and promote the development of this industry scientifically is an urgent problem to be solved at present.

Professor Zhang Heping, Inner Mongolia Agricultural University

Eating mushrooms helps reduce the risk of mild cognitive impairment

With the rapid aging of the population, the number of elderly people with dementia is expected to increase rapidly in the next 10 to 20 years.It will be a great challenge for the elderly to keep their brain healthy and cognitive function good.Professor Feng Lei of the National University of Singapore said, "mushroom intake can help reduce the risk of mild cognitive impairment."

Professor Feng Lei, National University of Singapore

According to its introduction, the cognitive protection function of mushrooms may be related to an ingredient called ergothione.Studies have shown that ergothione has antioxidant and anti-inflammatory effects and protects nerve cells, which is why older people who eat more mushrooms are less likely to suffer from mild cognitive impairment.

Breakthrough in the cultivation of Lentinus edodes and Morchella

"there is much room for improvement in per unit yield and quality of Lentinus edodes in China. The sustainable development of the industry is faced with eight scientific and technological problems: sawdust substitution of cultivation raw materials, strain degradation, efficient color conversion of bacteria bags, breeding of excellent varieties, water conservation and water supply of bacteria bags, regulation and control of cultivation environment, improvement of product flavor and rapid identification of strain quality."

At the meeting, Professor Bian Yinbing of Huazhong Agricultural University put forward a systematic solution to the eight scientific and technological problems and research strategies of Lentinus edodes industry.

Professor Bian Yinbing, Huazhong Agricultural University

The stability and repeatability of mushroom emergence has always been an insurmountable worldwide problem in the long history of artificial domestication of Morchella esculenta.

At the meeting, Gan Bingcheng, a researcher at the soil and Fertilizer Institute of Sichuan Academy of Agricultural Sciences, introduced that his team successively studied the artificial domestication and cultivation of 12 species of Morchella. Four species of Morchella were identified as saprophytic and cultivated species, and the stable emergence of Morchella was realized by inventing the cultivation technology of exogenous nutrition transformation bag.

Gan Bingcheng, researcher, soil and Fertilizer Research Institute, Sichuan Academy of Agricultural Sciences

Since the world's first approved new variety of Morchella "Sichuan Morchella No. 1" was bred in 2013, researcher Gan Bingcheng and his research group have successively bred 5 new varieties of Sichuan Morchella, which have been authorized for the protection of new plant varieties.

Through the research, innovation and application of matching strain propagation and efficient cultivation techniques, the research group successfully realized the commercial cultivation of Morchella in the field, leading and driving the rapid development of Morchella industry in the whole country.

The bad condition of spleen and stomach is related to intestinal flora.

The spleen is responsible for the transformation, absorption and transfer of dietary nutrients and water dampness (qi, blood and body fluid); the stomach is responsible for receiving and ripening the water valley (that is, the digestion process).

Professor Liu Fengbin, director of the first affiliated Hospital of Guangzhou University of traditional Chinese Medicine, introduced at the meeting that the coordination of spleen and stomach function is directly related to the function of the five internal organs of the human body.Therefore, the spleen and stomach plays an important role in the regulation of human nutrition, and the poor spleen and stomach is related to the intestinal flora of the human body.

Professor Liu Fengbin, Director of the first affiliated Hospital of Guangzhou University of traditional Chinese Medicine

Ganoderma lucidum spore polysaccharides are active in tumor immunity.

As one of the traditional rare edible and medicinal fungi, Ganoderma lucidum has been included in the Pharmacopoeia of the people's Republic of China and American Herbal Pharmacopoeia and treatment Summary. Because of its rich pharmacological activity, Ganoderma lucidum is widely used in the medical and health care industry.

Researcher Xie Yizhen, director of the Edible Fungi Center of Guangdong Institute of Microbiology, introduced at the meeting that Ganoderma lucidum spore polysaccharides showed a positive effect on tumor immunity, and it also pointed out that Ganoderma lucidum spore oil can promote the blood supply of the heart and inhibit the expression of heart failure genes.

Researcher Xie Yizhen, Director of Edible Fungi Center of Guangdong Institute of Microbiology

Selenium-rich Cordyceps shows bone protection and anti-tumor activity.

Pharmacological and clinical studies have shown that polysaccharides are one of the main bioactive components of Cordyceps sinensis Cs4, and have a wide range of health promotion and therapeutic effects, such as immune regulation, anti-tumor, and bone protection.

Using cordyceps polysaccharide as a stabilizer, Huang Jiaxing, an associate professor of Hong Kong Polytechnic University, and his team successfully prepared a new type of highly stable Cordyceps polysaccharide functionalized nano-selenium (Cs4-SeNPs).

Huang Jiaxing introduced at the meeting that this new type of cordyceps polysaccharide nano-selenium (Cs4-SeNPs) showed significant bone protection in vivo in cell and animal models.

The birth of Cs4-SeNPs is expected to develop a new type of high-quality, safe and empirical bone protectin for patients with climacteric osteoporosis in China, and contribute to the strengthening of national bone health.

Selenium is an important trace element necessary for human body.

A large number of studies have shown that selenium has a wide range of biological functions, such as antioxidant, anti-tumor, anti-inflammatory, anti-hypertension, hypoglycemic and so on.Using edible and medicinal fungi as carriers for selenium-rich research and the development of selenium-rich products is the current research hotspot.Professor Chen Fengfeng of Jinan University and his team found that selenium-rich Cordyceps militaris showed good antioxidant activity, anti-tumor activity, and can reduce the damage of normal lung cells caused by radiotherapy.

Professor Chen Fengfeng, Jinan University

In addition, based on the structural characteristics of fungal polysaccharides, the team functionalized nano-selenium to improve its physiological stability and targeting, and found that functional nano-selenium can be used as a tumor immune sensitizer with high efficiency and low toxicity. it can efficiently activate immune cells in tumor and its microenvironment and enhance the persistence of killing tumor.

Professor Chen Fengfeng said that combining it with low-dose radiotherapy can greatly improve the overall therapeutic effect of tumor and achieve multimodal tumor immunotherapy.

Intestinal flora is related to the occurrence of Alzheimer's disease.

The network regulation system of "intestinal microorganism-intestinal-brain axis" is an important part of the normal operation of the human body. "

Through experimental observation, Dr. Chen Diling, an associate researcher at Guangdong Institute of Microbiology, found that intestinal flora is related to the occurrence and development of AD (Alzheimer's disease).

Studies suggest that intestinal microorganisms and their metabolites participate in the occurrence and development of AD disease by affecting the host's functions such as oxidative stress, inflammation and autophagy.

In addition, the early intervention of dietary nutrition can be used as an important strategy for the prevention and delay of AD, a complex disease.

Dr. Chen Diling, Associate researcher of Guangdong Institute of Microbiology

The establishment of foodborne strain database can strengthen food risk early warning.

(Listeria monocytogenes) is an important foodborne pathogen with strong adaptability. Infection can cause septicemia, meningitis and other diseases, and the fatality rate is as high as 20% to 30%.

Dr. Chen Moutong, Associate researcher of Guangdong Institute of Microbiology

Dr. Chen Mutong, associate researcher of Guangdong Institute of Microbiology, collected 4300 food samples from 43 cities or regions in China for risk identification of Listeria monocytogenes. The results showed that the overall contamination rate of Listeria monocytogenes was 16.5%.

Through the establishment of the resource database and risk identification database of Listeria monocytogenes in China, it can provide basic data for the rapid detection technology, hazard mechanism, risk early warning and prevention and control technology of Listeria monocytogenes in China.

Top scientists at home and abroad gathered at the conference to plan and promote scientific and technological innovation in edible and medicinal fungi from a global perspective, so as to provide forward-looking and strategic guidance for the development of the microbial seed industry.

At this new strategic opportunity of Guangdong-Hong Kong-Macau Greater Bay Area's construction, the convening of the Fifth China Conference on Edible and Medicinal Fungi is of far-reaching significance to help Guangdong-Hong Kong-Macau Greater Bay Area occupy the innovative highland of microbial resources research and promote the development and upgrading of the industry chain of edible and medicinal fungi.

Tidbits of the conference: